Rb-Driven Transcription Limits Tumour-Suppressive Effects in Breast Cancer

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Science

13 August 2026 at 12:32 am

Rb-Driven Transcription Limits Tumour-Suppressive Effects in Breast Cancer

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Summary

Research published in Nature indicates that CDK4/6 inhibition redirects Rb chromatin occupancy, activating oestrogen-responsive genes and counteracting its own tumour-suppressive effects in breast cancer.

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